Protocol summary

Study aim
The aim of the study is to assess the effects of early phase protocol in anterior cruciate ligament reconstruction patients in addition to conventional physical therapy protocol.
Design
Two arm parallel group randomized trial with blinded postoperative care and outcome assessment
Settings and conduct
Study will be conducted at Hayatabad medical complex, Khyber teaching hospital and Lady reading hospital, Peshawar.
Participants/Inclusion and exclusion criteria
Inclusion criteria: Patient underwent through ACL reconstruction surgery using hamstring and peroneus longus graft, Both males and females, aged 18 to 40 years. Exclusion criteria: Patients with medial collateral ligament injuries, meniscal injuries and infections, Patients with known neurological diseases, Patients with known cognitive impairment.
Intervention groups
Group A will receive routine/conventional therapy while Group B will receive conventional plus Fowler Kennedy’s protocol. All the participants will be assessed for base line measurements i.e. range of motion to the opposite knee, joint swelling, neuromuscular control and muscle strength. Both groups will be followed for two weeks.
Main outcome variables
1. Lower Extremity Functional Score (LEFS) 2. Numeric Pain Rating Scale (NPRS) 3. Goniometer for Range of motion 4. Cincinnati knee rating system (CKRS) 5. Tegner Lysholam knee activity scale

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20221214056821N1
Registration date: 2023-01-07, 1401/10/17
Registration timing: registered_while_recruiting

Last update: 2023-01-07, 1401/10/17
Update count: 0
Registration date
2023-01-07, 1401/10/17
Registrant information
Name
Mashal Gul
Name of organization / entity
Khyber Medical University
Country
Pakistan
Phone
+92 91 5843042
Email address
mashal.gul@ncs.edu.pk
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2022-12-20, 1401/09/29
Expected recruitment end date
2023-04-20, 1402/01/31
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effectiveness of early phase rehabilitation on outcomes of anterior cruciate ligament reconstruction in patients of tertiary care hospitals of Peshawar
Public title
Rehabilitation for anterior cruciate ligament reconstruction patients
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Patient underwent through ACL reconstruction surgery using hamstring and peroneus longus graft Both males and females, aged 18 to 40 years
Exclusion criteria:
Patients with medial collateral ligament injuries, meniscal injuries & infections. Patients with known neurological diseases Patients with known cognitive impairment
Age
From 18 years old to 40 years old
Gender
Both
Phase
3
Groups that have been masked
  • Outcome assessor
Sample size
Target sample size: 40
Randomization (investigator's opinion)
Randomized
Randomization description
Subjects will be randomly assigned to one of two groups using sealed envelope method: one (the experimental group) receiving the intervention, and the other (the comparison group or control) receiving an alternative (conventional) treatment
Blinding (investigator's opinion)
Single blinded
Blinding description
Due to nature of study, it will not be feasible to blind therapist and subjects. However, assessor, who will assess pre and post measurements, will be blinded
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
AS&RB (Advanced Studies & Research Board) and ethical committee of Khyber Medical University
Street address
Phase 5 Hayatabad
City
Peshawar
Postal code
25000
Approval date
2021-10-19, 1400/07/27
Ethics committee reference number
KMU/AS&RB/MSPT/2021/27

Health conditions studied

1

Description of health condition studied
ACL reconstruction rehabilitation
ICD-10 code
S83.50
ICD-10 code description
Sprain of unspecified cruciate ligament of knee

Primary outcomes

1

Description
Lower Extremity Function
Timepoint
Baseline Assessment and Assessment after 2 weeeks of intervention
Method of measurement
Lower Extremity Function Score

2

Description
Pain
Timepoint
Baseline Assessment and Assessment after 2 weeks of intervention
Method of measurement
Numeric Pain rating Scale

3

Description
Range of motion
Timepoint
Baseline Assessment and Assessment after 2 weeks of intervention
Method of measurement
Goniometer

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Heel slides (slider board), Supine with legs up wall heels slides with gravity assisted, Bike pendulums: high seat circles forward and backward full circles lower seat Sitting passive leg extension with roll under heel OR prone leg hangs off end of bed Seated calf stretch with towel, knee bent (soleus), knee straight (gastrocnemius), Seated hamstring stretch (back straight), Quadriceps and hamstring co-contraction, Quadriceps isometrics in standing, sitting, lying +/– muscle stimulation or biofeedback, Sit to stand progress by gradually decreasing height of seat, Static lunge forward/side, Mini wall squat (30°), Side lying abduction and adduction, Gluteal squeezes supine or standing, Prone hip extension, Standing hip flexion and extension, abduction/adduction, Ankle pumping +/– with leg elevation, Standing calf raises with and without support, Single leg stance 30 to 60 seconds, Wobble boards with support (table, bars, poles) through full ROM: side to side, forward and backward, Weight shifting: side to side and forward and backward, Progress from 2 crutches to 1, always maintaining normal walking pattern, Ice 15-25 minutes, Interferential current therapy (pain relief), Muscle Stimulation.
Category
Rehabilitation

2

Description
Control group: Icing 10-15 minutes, Gluteal squeezes supine or standing, Prone hip extension, standing hip flexion and extension, abduction and adduction, Ankle pumping +/– with leg elevation, standing calf raises with/without support, Single leg stance 30-60 seconds.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Hayatabad Medical Complex, Peshawar
Full name of responsible person
Khalid Khan
Street address
Phase-4 Phase 4 Hayatabad, Peshawar, Khyber Pakhtunkhwa
City
Peshawar
Postal code
25000
Phone
+92 91 9217140
Email
khalidleokhan@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Khyber Medical University
Full name of responsible person
Mujeeb Ur Rahman
Street address
F1 Phase-6 Rd, Phase 5 Hayatabad, Peshawar, Khyber Pakhtunkhwa
City
Peshawar
Postal code
25100
Phone
+92 333 2251226
Email
mujeeb.rahman@kmu.edu.pk
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Khyber Medical University
Proportion provided by this source
50
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
NCS University System
Full name of responsible person
Mashal Gul
Position
Senior Lecturer
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
N Canal Rd, Abdarra, Peshawar, Khyber Pakhtunkhwa
City
Peshawar
Province
Khyber Pakhtunkhwa
Postal code
25000
Phone
+92 91 9331105
Email
mashal.gul@ncs.edu.pk

Person responsible for scientific inquiries

Contact
Name of organization / entity
Rehman Medical Institute, Peshawar
Full name of responsible person
Sarmad Saeed Khattak
Position
Senior Physical Therapist
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
XCRP+W7C, 5-B/2 Shaukat Khanum Rd, Phase 5 Hayatabad, Peshawar, Khyber Pakhtunkhwa
City
Peshawar
Province
Khber Pakhtunkhwa
Postal code
25100
Phone
+92 91 5838666
Email
sarmad.saeed@rmi.edu.pk

Person responsible for updating data

Contact
Name of organization / entity
NCS University System
Full name of responsible person
Mashal Gul
Position
Senior Lecturer
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
N Canal Rd, Abdarra, Peshawar, Khyber Pakhtunkhwa
City
Peshawar
Province
Khyber Pakhtunkhwa
Postal code
25000
Phone
+92 91 9331105
Email
mashal.gul@ncs.edu.pk

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
The institute as well as my patients I am working with is not allowing me to share data
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
Loading...