The effect of Endoactivator on Postoperative Pain in necrotic teeth with Apical Periodontities, a Clinical Trial Study

The effect of endoactivator on pain after treatment of necrotic teeth with chronic apical periodontitis

The clinical trial is parallel, single-blind, with a placebo, randomized, on 44 patients. Randomization will be done using a table of random numbers, and allocation concealment with the sealed envelope method.

This is a clinical trial study on 44 patients with necrotic teeth with chronic apical periodontitis score 2 or 3, which is diagnosed by radiography and negative cold test, single root and single canal, who refer to Azad Faculty of Dentistry in Tehran for routine endodontic treatment. will be done Washing is done in both groups using 40 ml of 5.0% NaOCl. Standard washing is done using a 5 cc 30 gauge syringe and a side hole made of stainless steel. For the induction group, the tip of the device continuously injects 5.0% NaOCl into the channel entrance for one minute. To check the pain after the treatment, we ask the patients to evaluate the intensity of the pain after the operation on the VAS scale at 8, 24, 48, and 72 hours after the visit.

Inclusion criteria: age between 18 and 65 years, a necrotic tooth with chronic apical periodontitis score 2 or 3. Exclusion criteria: pregnant or lactating patients, patients who are allergic to non-steroidal anti-inflammatory drugs.

For the control group, standard washing is done using a 5 cc 30 gauge syringe and a side hole made of stainless steel. For the induction group, the tip of the device continuously injects 0.5% NaOCl into the canal entrance for one minute.

Occurrence of Postoperative Pain

In this study, we will use the simple randomization method of the random number table type. Since the total number of study subjects is 44 people and a two-digit number, we give each person a two-digit code. Then, to select sample people from the table, by closing the eyes and putting the tip of the pen on the table, starting from a point of the table in the direction of the row or column, and taking into account that the code of each person is two digits, we start choosing two-digit numbers. The selected number is actually the code of an individual from the community that is selected as a sample. This continues until the number of people in the inducer group sample (22 people) can be chosen smaller than 44..In order to conceal, we use concealment allocation, which is the method used to perform a random sequence on the study participants, in such a way that the assigned group is not known before the allocation of the individual. Using opaque envelopes sealed with a random sequence (envelopes opaque, sealed, numbered sequentially), in this method, each of the random sequences created is recorded on a card, and the cards are placed inside the envelopes in order They are placed.In order to maintain a random sequence, the outer surface of the envelopes is numbered in the same order. Finally, the lids of the envelopes are glued and placed in a box. At the time of registration of participants, based on the order of entry of eligible participants into the study, one of the envelopes will be opened and the assigned group of that participant will be revealed.

After obtaining the consent form and general introduction of the study groups to the participants, the information that can cause the test result to deviate remains hidden from the participant's view, but the person responsible for conducting the test is aware of them and the study is conducted in a single blind manner.