This study aims to compare the efficacy of topical Procapil 5% versus topical Minoxidil 5% in the treatment of androgenetic alopecia.
Design
Community based, parallel group, single blinded, RCT
Settings and conduct
In this study 38 patient with moderate to severe AGA are enrolled after explaining thoroughly the course and purpose of study. Patients are randomly assigned one of the two groups, one receiving topical Procapil 5% and the other receiving topical Minoxidil 5% solution twice daily for 6 months.
Participants/Inclusion and exclusion criteria
Inclusion criteria A. Clinical diagnosis of AGA B. Age range of 18 - 55 years, C. Patients who haven’t received topical or systemic treatments for AGA within 3 months prior to the study. D. Patient who gave consent for the study Exclusion criteria A. Those with other causes of hair loss such as fungal infection such as taenia capitis, inflammatory or scarring alopecia, hyper-androgenism or other hormonal disorders B. Hypersensitive to the medications C. A history of severe systemic disease (renal, cardiovascular hepatic and lungs). D. Pregnant or breastfeeding patients
Intervention groups
Intervention group 1: Patients in the first group will be treated with Topical Procapil 5% (1 cc twice daily). Intervention group 2: Patients in the second group will receive topical Minoxidil 5% (1 cc twice daily) for 6 months.
Main outcome variables
Number of hairs, Change in photographic pictures and patient satisfaction score.
General information
Reason for update
Acronym
AGA Androgenetic Alopecia
IRCT registration information
IRCT registration number:IRCT20210823052264N10
Registration date:2024-09-26, 1403/07/05
Registration timing:registered_while_recruiting
Last update:2024-09-26, 1403/07/05
Update count:0
Registration date
2024-09-26, 1403/07/05
Registrant information
Name
Najia Ahmed
Name of organization / entity
PNS shifa
Country
Pakistan
Phone
+92 81 2864092
Email address
najiaomer@yahoo.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2024-07-01, 1403/04/11
Expected recruitment end date
2024-12-31, 1403/10/11
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of Efficacy of Topical Procapil 5% Versus Topical Minoxidil 5% in Androgenetic Alopecia
Public title
Comparison of Efficacy of Topical Procapil 5% Versus Topical Minoxidil 5% in Androgenetic Alopecia
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Clinical diagnosis of AGA score 2-5 on Norwood-Hamilton Classification
Age range of 18 - 55 years
Patients who haven’t received topical or systemic treatments for AGA within 3 months prior to the study.
Patient who gave consent for the study
Exclusion criteria:
Those with other causes of hair loss such as fungal infection such as taenia capitis, inflammatory or scarring alopecia, hyper-androgenism or other hormonal disorders
Hypersensitive to the medications
A history of severe systemic disease (renal, cardiovascular hepatic and lungs)
Pregnant or breastfeeding patients
Age
From 18 years old to 55 years old
Gender
Both
Phase
3
Groups that have been masked
Participant
Data analyser
Sample size
Target sample size:
38
Randomization (investigator's opinion)
Randomized
Randomization description
Simple randomization with Lottery method (using sealed envelops)
Blinding (investigator's opinion)
Double blinded
Blinding description
Double blinded study (participants and data analyzer are blinded)