1. Home
  2. Approved trials
  3. » فارسی

Comparing the effects of local, functional, and mental fatigue protocols on isokinetic strength, balance, and performance in healthy athletes and with anterior cruciate ligament reconstruction

Protocol summary

Study aim
Comparison of the effects of local, functional, and mental fatigue protocols on quadriceps to hamstring strength ratio at speeds of 60, 180, and 300 degrees per second, static and dynamic balance, and landing performance in healthy athletes and with anterior cruciate ligament reconstruction.
Design
The clinical trial will have a group of 12 athletes with ACL reconstruction, and a group of 12 healthy athletes. These samples will be selected purposively.
Settings and conduct
The location of the study is the Corrective Exercise Laboratory, Faculty of Sport and Health Sciences, University of Tehran. The study will be conducted in the form of a pre-test and post-test. The study variables will be measured before and after applying the fatigue protocols.
Participants/Inclusion and exclusion criteria
Male athletes with anterior cruciate ligament reconstruction of the dominant leg have a non-contact ACL injury mechanism. The surgical method for anterior cruciate ligament (ACL) reconstruction will involve an open procedure using a hamstring autograft. Post-rehabilitation, the participants must have a physical activity level of 6 or higher according to the Tegner Activity Scale upon return to sports. Full range of motion in the knee Body mass index (BMI) between 18 and 25 will be required.
Intervention groups
Interventions include local, functional, and mental fatigue protocols. The local fatigue protocol is applied using an isokinetic machine. The functional fatigue protocol is applied using the L Drill fatigue protocol. The mental fatigue protocol is applied using the Stroop protocol.
Main outcome variables
Types of local, functional, and mental fatigue can affect muscle strength, landing performance, joint position sense, and balance, and this effect can differ between healthy and ACL reconstruction groups.

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20191214045729N2
Registration date: 2025-06-24, 1404/04/03
Registration timing: prospective

Last update: 2025-06-24, 1404/04/03
Update count: 0
Registration date
2025-06-24, 1404/04/03
Registrant information
Name
Mohammad Hamzeh
Name of organization / entity
The University of Tehran
Country
Iran (Islamic Republic of)
Phone
+98 38 3262 2846
Email address
m.hamzeh13755@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2025-08-06, 1404/05/15
Expected recruitment end date
2026-01-05, 1404/10/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing the effects of local, functional, and mental fatigue protocols on isokinetic strength, balance, and performance in healthy athletes and with anterior cruciate ligament reconstruction
Public title
Comparing the effects of local, functional, and mental fatigue protocols on muscle strength, balance and performance in healthy athletes and with anterior cruciate ligament reconstruction.
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
The samples were from athletes in sports with shearing, jumping, and landing movement patterns who had regular sports activity and at least 3 years of experience. The mechanism of ACL injury is non-contact and occurs in jumping and landing movement patterns or shearing movements. The surgical procedure is anterior cruciate ligament reconstruction with hamstring autograft. Have completed various levels of rehabilitation and rehabilitation courses. The physical activity level of individuals after the rehabilitation process and return to sports should be a score of 6 or higher based on the Tigner questionnaire. Full range of motion in knee flexion and extension movements Body mass index between 18 - 25
Exclusion criteria:
Any neurological, cardiovascular, metabolic, rheumatic or vestibular disease. Frequent use of painkillers and drugs that affect the person's balance Consumption of any caffeine, energy drinks, or alcohol 24 hours before performing the fatigue protocol Performing intense physical activity 24 hours before the implementation of the fatigue protocol Having any history of injury or surgery to the hip, ankle, foot, or opposite knee injury Having any mental health problems, such as depression or anxiety
Age
From 18 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 24
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Other
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Ethics Committees of Tehran University - Faculty of Sport Sciences and Health
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Approval date
2025-05-11, 1404/02/21
Ethics committee reference number
IR.UT.SPORT.REC.1404.074

Health conditions studied

1

Description of health condition studied
Anterior Cruciate Ligament Reconstruction
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Quadriceps to hamstring strength ratio
Timepoint
At the beginning of the study (before the start of the intervention) and 7, 14 and 21 days after the start of the study (after each fatigue protocol applied at 7-day intervals).
Method of measurement
Isokinetic

Secondary outcomes

1

Description
Knee Flexion and Extensor Peak Torque
Timepoint
At the beginning of the study (before the start of the intervention) and 7, 14 and 21 days after the start of the study (after each fatigue protocol applied at 7-day intervals).
Method of measurement
Isokinetic

2

Description
Landing performance
Timepoint
At the beginning of the study (before the start of the intervention) and 7, 14 and 21 days after the start of the study (after each fatigue protocol applied at 7-day intervals).
Method of measurement
Landing Error Scoring System

3

Description
Joint Position Sense
Timepoint
At the beginning of the study (before the start of the intervention) and 7, 14 and 21 days after the start of the study (after each fatigue protocol applied at 7-day intervals).
Method of measurement
Isokinetic

4

Description
Postural Stability
Timepoint
At the beginning of the study (before the start of the intervention) and 7, 14 and 21 days after the start of the study (after each fatigue protocol applied at 7-day intervals).
Method of measurement
Biodex Balance System

Intervention groups

1

Description
Intervention group one: Local fatigue: To induce localized fatigue, the Biodex isokinetic dynamometer (System 4 Pro™ model) will be used. In this experiment, each participant will undergo six test stages. The first three stages involve determining the maximum torque at three angular velocities: 60, 180, and 300 degrees per second. The criterion for achieving fatigue at each speed is a reduction in torque to below 50% of the individual's maximal voluntary torque at that specific speed.
Category
Other

2

Description
Intervention group two: Functional fatigue : To induce functional fatigue, a functional agility short-term fatigue protocol will be used. This protocol consists of the following four components: Step-up L-drill Countermovement jump Agility ladder drill. Based on previous studies, participants are required to complete all four sets of the protocol consecutively in order to induce a state of fatigue. The entire sequence is estimated to last approximately six minutes.
Category
Other

3

Description
Intervention group three: Mental fatigue: The mental fatigue protocol will be conducted using the Stroop test.To induce mental fatigue, a 30-minute Stroop task will be employed. The Stroop mental fatigue task is essentially a color-word interference test administered during the mental fatigue session. In this task, color words ("red," "blue," "green," and "yellow") are presented on a screen in either congruent or incongruent formats.Participants are encouraged to exert maximal effort to complete as many items as possible within the 30-minute period.The Stroop task will be administered using the DMDX software on the same display and at the same distance.
Category
Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Laboratory of corrective exercise Faculty of Sports and Health Sciences University of Tehran
Full name of responsible person
Ali Mirabedi
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Phone
+98 21 7308 8351
Fax
+98 21 8802 1527
Email
infosport@ut.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
The University of Tehran
Full name of responsible person
Hooman Minoonejad
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Phone
+98 21 7308 8351
Email
h.minoonejad@ut.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
The University of Tehran
Proportion provided by this source
5
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
The University of Tehran
Full name of responsible person
Mohammad Hamzeh Shalamzari
Position
Ph.D Student
Latest degree
Ph.D.
Other areas of specialty/work
Corrective Exercise and Sport Injuries
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Phone
+98 21 6111 8928
Email
m.hamzeh13755@ut.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
The University of Tehran
Full name of responsible person
Hooman Minoonejad
Position
Associate Professor
Latest degree
Ph.D.
Other areas of specialty/work
Corrective Exercise and Sport Injuries
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Phone
+98 21 6111 8928
Email
h.minoonejad@ut.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
The University of Tehran
Full name of responsible person
Mohammad Hamzeh Shalamzari
Position
Ph.D Student
Latest degree
Master
Other areas of specialty/work
Corrective Exercise and Sport Injuries
Street address
Faculty of Physical Education and Sport Sciences, between 15th and 16th St., North Kargar st., Tehran, Islamic Republic
City
Tehran
Province
Tehran
Postal code
1439955975
Phone
+98 21 6111 8928
Email
m.hamzeh13755@ut.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Not applicable
Analytic Code
Not applicable
Data Dictionary
Not applicable
Title and more details about the data/document
All data can be shared after de-identifying individuals.
When the data will become available and for how long
The access period begins 8 months after the results are published.
To whom data/document is available
The data is accessible to all scientific and industrial people.
Under which criteria data/document could be used
The data is accessible to all scientific and industrial people.
From where data/document is obtainable
To receive the data, they can apply to the following email address: m.hamzeh13755@ut.ac.ir Also, they can contact Mohammad Hamzeh at the following number: 00989138790757
What processes are involved for a request to access data/document
After sending the applicant's email and code assigned to the subject at the time of testing, his data will be sent.
Comments
Loading...