The Combined effect of high-intensity functional training and terminalia chebula extract on liver enzymes, metabolic syndrome indices, and physical fitness factors in women with metabolic syndrome

The combined effect of high-intensity functional training and Terminalia chebula extract on improving liver enzymes, metabolic syndrome indices and physical fitness factors in women with metabolic syndrome

The statistical population will include women with metabolic syndrome aged 35 to 45 years. 60 people will be selected by random sampling from among the population who volunteer to participate in the present study. The sample size was determined using G-power software.

The subjects were subjected to research interventions for 8 weeks, and after 8 weeks, the desired factors will be examined to obtain results. The research is being conducted in Farsh province, Eqlid city, Rastkar laboratory, and the workers' sports hall.

: blood triglycerides above 150 mg/dL, HDL less than 50 mg/dL, waist circumference more than 88 cm, fasting blood glucose above 100 mg/dL, and systolic blood pressure above 130 mmHg or diastolic blood pressure above 85 mmHg. Also, if the subjects have cardiovascular, respiratory, nephrotic, hepatic, and neurological disorders and consume alcohol and cigarettes, they will not be allowed to enter and participate in the present study.

The training groups will perform HIFT exercises for eight weeks, three sessions per week, each session lasting 60 to 90 minutes. and the subjects in the supplement group will also take capsules containing black cumin extract at a dose of 500 mg twice daily (every 12 hours) with two glasses of water. The subjects in the control group will carry out daily activities for 8 weeks.

Improvement of liver enzymes, improvement of metabolic syndrome indicators (lipoprotein, abdominal obesity) and physical fitness factors

In this study, after initial recruitment and screening, eligible participants (women with metabolic syndrome) will enter the allocation phase. First, blood tests and measurements of required factors will be performed according to the protocol. Then, all eligible individuals, without any priority, precedence, or specific criteria for group entry, will be equally and with equal probability assigned to four research groups. The randomization process will be conducted using simple randomization. For this purpose, a computer-generated numerical list using Random Allocation Software will be used. This list will determine the allocation of individuals to one of the four groups (exercise, exercise + supplement, supplement, control). In this method, all individuals will have an equal chance of being placed in any of the groups, and no systematic differences in baseline characteristics will be created between the groups. Also, the data collector will not be informed of the randomization sequence to maintain at least a single-blind level.

Data collectors, such as the nurse who conducts blood tests, do not know who was in the control, exercise, supplement, and exercise groups.

No further information available.