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Study aim: Comparison of the effect of remifentanil and dexmedetomidine on surgeon satisfaction from surgical field and bleeding in rhinoplasty Design: Double-blind randomized clinical trial Settings and conduct: The drugs are prepared in the operating room by a nurse who is unaware of the type of study with label A in the dexmedetomidine group and label B in the remifentanil group and are given to a person who is unaware of the specialization of the groups for injection. The person assessing patients and patient satisfaction at the end of the study is also unaware of the allocation of study groups. Participants/Inclusion and exclusion criteria: Inclusion criteria:18-45 y/o, Patients undergoing rhinoplasty surgery Exclusion criteria: Patients with liver dysfunction, Renal dysfunction, Any known allergy or hypersensitivity to study drugs, analgesics abuse, opium addiction, Diabetes , Hemorrhagic disease, Using anticoagulants, Cerebrovascular disease, Heart block, Cardiovascular disease. Intervention groups: In the Intervention group one patients will receive 1 μg / kg dexmedetomidine (PFIZER, USA) for 20 minutes and at the same time as induction begins with a dose of 0.6 μg / kg and continues until the end of the operation. In the Intervention group two simultaneously with the induction of anesthesia, in the remifentanil group (EXIR, IRAN), remifentanil infusion of 0.25 μg is started. It continued until the end of the operation. Main outcome variables: Intraoperative bleeding, pain,surgeon satisfaction
IRCTID: IRCT20141009019470N112
  1. The effect of medication including dexmedetomidine + remifentanil VS remifentanil on bleeding during rhinoplasty surgery
  2. Comparison of the effect of low-dose naloxone infusion on hemodynamic factors and surgical field bleeding in patients under general anesthesia with remifentanil and propofol infusion.
  3. Comparison of the Effect of Dexmedetomidine, Remifentanil and Metoral on Reducing Bleeding and Surgery Satisfaction During Rhinoplasty
  4. Comparative study of the dexmedetomidine and magnesium sulphate in controlled hypotension in patients candidate for rhinoplasty operation
  5. Comparative effects of acupuncture and placebo acupuncture in reducing intraoperative bleeding in open rhinoplasty surgery in patients 18 to 45 years, ASA class1 in Vali Asr Operation Room, Imam Khomeini Hospital 1390-91 years, a randomized clinical trial.
  6. Comparison of the effect of two different anesthesia methods with Remifentanil and Dexmedetomidine on the amount of bleeding during surgery and the visual in endoscopic sinus surgeries
  7. Comparison of hemodynamic changes due to intravenous or inhalational anesthtics for deep vitrectomy surgery
  8. Comparison of the effect of dexmedetomedine and remifentanil in reducing paranasal sinus surgery bleeding: a double-blind randomized clinical trial
  9. Effect of Intravenous Dexmedetomidine on Inflammatory factors in Patients undergoing Total Abdominal Hysterectomy
  10. Comparison of the effect of tranexamic acid and dexmedetomidine on intra-operative bleeding in patients candidate for rhinoplasty
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