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Study aim: Comparison of the therapeutic effect of the combination of Erbium YAG laser and stromal vascular fraction (SVF), the combination of Erbium YAG laser and platelet-rich plasma (PRP) and Erbium YAG laser alone in the treatment of striae Design: Clinical trial with control group, with parallel groups, double-blind, randomized with sealed envelopes, phase 2-3 on 10 patients (30 lesions) Settings and conduct: In this study, 10 patients with at least three striae will be treated with Erbium YAG Laser in one session. Then, in the same session, one side is randomly injected with SVF, one side is injected with PRP, and the third side is injected with placebo. Injections are done with syringes of the same shape and color, and the patient, as well as the doctor evaluating the results and the statistician are blinded. Participants/Inclusion and exclusion criteria: Inclusion criteria: The diagnosis of stria distensa based on the diagnosis of a dermatologist, Age less than 50 years and more than 18 years Exclusion criteria: Using any treatment method to remove striae in the last three months, Presence of lesions and skin diseases such as skin cancer or infections, Presence of collagen vascular diseases, Pregnancy and lactation, Using steroids or immunosuppressive drugs Intervention groups: 3 groups: combination of Erbium YAG laser and stromal vascular fraction (SVF), the combination of Erbium YAG laser and platelet-rich plasma (PRP) and Erbium YAG laser alone Main outcome variables: Examining the level of effectiveness based on the Vancouver scale
IRCTID: IRCT20220322054341N2
  1. Comparison of the effect of combination Erbium YAG laser and SVF therapy with Erbium YAG laser alone in the treatment of striae
  2. Comparison of therapeutic effect of nanofat injection alone and nanofat with Stromal Vascular Fraction (SVF), Platelet Rich Plasma (PRP) and ND-YAG laser in improving darkening and rejuvenation under the eye
  3. Evaluation of the effectiveness of nanofat along with Stromal vascular fraction (SVF) and Platelet Rich plasma (PRP) in facial rejuvenation and dark circles around the eyes
  4. Investigating The Effect of Erbium yag and Nd yag Laser and comparing to the Er:yag on Striae Alba
  5. Comparison of the Effectiveness of Microneedling Therapy with CO2 Fractional Leaser therapy for theTreatment of Striae Distensa in Patients with Striae Distensae
  6. Evaluation and comparison of the effect of simultaneous injection of Stromal Vascular Fraction with fractional CO2 laser in the treatment of burn scar
  7. Evaluation and comparison of the Efficacy of Stromal Vascular Fraction (SVF) Combined with Non-Cross-Linked Hyaluronic Acid Versus Platelet-Rich Plasma (PRP) combined with Non-Cross-Linked Hyaluronic Acid in the treatment of patients with atrophic acne scars undergoing fractional CO₂ Laser therapy
  8. Investigating the effect of SVF gel (Stromal Vascular Fraction (SVF) + non cross-linked hyaluronic acid) on the periorbital rejuvenation and comparing it with SVF injection alone
  9. Therapeutic impact of Adipose-derived Stromal Vascular Fraction And Platelet-rich plasma on non-operative treatment of osteochondral lesions of the talus: A Randomized Controlled Trial
  10. Comparison of the efficacy, safety and satisfaction of adipose derived stromal vascular fraction cells injection and 665nm low level diode laser hat in the treatment of androgenetic alopecia
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