Evaluation of Extremely Low Frequency Electromagnetic Fields Effects on Oxidative Stress and Reducing the effects of Oxidative Stress by Intervention of Vitamin E and C in Shaheed Bastami Power Plant’s Workers; A Duble Blind, Randomized Clinical Trial Study; 2017

The present study aimed at determining the effect of exposure to Extremely Low Frequency Electromagnetic Fields (ELF-EMFs) on oxidative stress and feasibility using of vitamins E and C as a treatment solution in order to reduce the effects of oxidative stress. The design of this study is Randomized double-blind study, non-placebo control and single-center. The population will be Shaheed Bastami power plant’s employees who directly exposed to ELF-EMFs of high voltage lines. The inclusion criteria are having at least one year of experience, working full time at the power plant and the range of age is 20 to 50 years of age. The exclusion Criteria are the people with hypertension according to WHO, haven’t treated by antioxidant dietary supplements and drugs with antioxidant properties and not using vitamins and antioxidants, such as vitamin E, C and beta-carotene and selenium. Sample size is 95 of Shaheed Bastami power plant’s employees. The people randomly divided into equal four groups in two stages based on block randomization. First group a tablet vitamin E 400 IU/day, second group a tablet vitamin C 1000 mg/day, third group a tablet containing vitamin E and C, 400 IU/day and 1000 mg/day respectively and forth group non-intervention during three months. Main outcomes are oxidative stress including Malondialdehyde, Superoxide dismutase, Catalase, Glutathione, Ceruloplasmin and Total Antioxidant Capacity.

The study has founded by Shahroud university of Medical Sciences