All patients in our selected population were diagnosed with polycystic ovary syndrome according to Rotterdam diagnostic criteria with the diagnosis of the gynecologist.Having at least two of the three following symptoms:1-Abnormal menstrual cycles (oligomenorrhea, amenorrhea)2- Polycystic ovary in ultrasound3- Clinical signs of hyperandrogenism (Acne- Hirsutism) or biochemical symptoms of hyperandrogenism.
Women aged 20-40 years
Body Mass Index (BMI) range: 30-40 Kg/m2
Moderate activity level
Only OCP consumer (estrogen and progesterone combination pills). All participants will only receive OCP.
Willingness to participate in the study
Pregnancy(tendency to become pregnant) or lactation
Having any illness that affecting the studied variables (such as liver disease, thyroid disease, cardiovascular disease, renal disease, gastrointestinal disease , Cushing's syndrome,adrenal hyperplasia, androgen-secreting tumors , hyperprolactinemia).
Insulin infusion and intakes of blood pressure regulating drugs, statins and or drugs that affect insulin resistance (such as metformin), thiazolidinedione, anti androgens.
Using of any vitamin and mineral supplements and or antioxidants or being under certain diets at least two months before the study.
Any changes in the therapeutic protocol during the study