History
# Registration date Revision Id
4 2021-01-31, 1399/11/12 169665
3 2021-01-26, 1399/11/07 168856
2 2019-10-24, 1398/08/02 109060
1 2019-07-16, 1398/04/25 97060
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  • Protocol summary

    The randomized controlled trial, with parallel groups, single-blind
    The randomized controlled trial, with parallel groups
    کارآزمایی بالینی تصادفی شده، با گروه های موازی، یک سویه کور
    کارآزمایی بالینی تصادفی شده، با گروه های موازی
    This study will be carried out at the Cancer Institute of Imam Khomeini Hospital. Question Prompt list will be provided to eligible patients, and finally, shared decision making, self-efficacy in decision making and Preferences in Participation will be measured. This study will be single-blind. data from two groups will be coded and delivered to the statistical analyst.
    This study was carried out at the Cancer Institute of Imam Khomeini Hospital. Question Prompt list was provided to eligible patients, and finally, shared decision making, decision self-efficacy, and Preferences for participation were measured. Data, from two groups, was coded and delivered to the statistician.
    این مطالعه در انستیتو کانسر بیمارستان امام خمینی(ره) انجام خواهد شد. لیست آماده سوالات به بیماران واجد شرایط ارائه می شود و در نهایت تصمیم گیری مشارکتی، خودکارآمدی در تصمیم گیری و ترجیح به مشارکت اندازه گیری خواهد شد. این مطالعه یک سو کور خواهد بود بدین صورت که داده های مربوط به دو گروه کدگذاری شده به تحلیل گر آماری تحویل داده می شوند.
    این مطالعه در انستیتو کانسر بیمارستان امام خمینی(ره) انجام خواهد شد. لیست آماده سوالات به بیماران واجد شرایط ارائه شد و در نهایت تصمیم گیری مشارکتی، خودکارآمدی در تصمیم گیری و ترجیح به مشارکت اندازه گیری شد. داده های مربوط به دو گروه کدگذاری شده به تحلیل گر آماری تحویل داده شد.
    Inclusion criteria: Ability to read and write the Persian language,to receive for chemotherapy, radiation therapy or both, age 18 and above, patient's willingness to participate in research, knowledge of breast cancer diagnosis for itself. Exclusion criteria: Patient's reluctance to continue to collaborate in research, mental illness that impedes participation in decision making or informed consent.
    Inclusion criteria: patients with breast cancer who were referred for adjuvant/ neoadjuvant treatment following tumor resection, knowing their diagnosis of breast cancer, able to read and write Persian; and age 18 years or older Exclusion criteria: a history of psychiatric illness that would prevent them from participating in treatment decision-making, metastatic breast cancer, and reluctance to participate in research
    شرایط ورود: سن 18 سال و بالاتر، توانایی خواندن و نوشتن به زبان فارسی، اطلاع از تشخیص سرطان پستان برای خود، دریافت پیشنهاد ادامه درمان با شیمی درمانی، رادیو تراپی و یا هر دوی آنها، تمایل مددجو به مشارکت در پژوهش شرایط عدم ورود: ابتلا به بیماری های روانی که مانع مشارکت در تصمیم گیری یا دادن رضایت آگاهانه شود، عدم تمایل به شرکت در مطالعه.
    شرایط ورود: 1. بیماران مراجعه کننده برای درمان adjuvant و neoadjuvant (بعد از جراحی برداشت تومور) 2. توانایی خواندن و نوشتن به زبان فارسی 3. سن 18 سال و بالاتر 4. اطلاع از تشخیص سرطان پستان برای خود شرایط عدم ورود: 1. ابتلا به بیماری های روانی که مانع از استقلال در تصمیم گیری برای درمان خود شود 2. ابتلا به سرطان متاستاتیک پستان 3. عدم تمایل به شرکت در مطالعه
    The intervention group will benefit from the QPL and the control group will receive routine care. The QPL will be an organized list of questions that clients can ask their answers at the next appointment with their physician or answer through the WhatsApp messenger, Soroush, And Eita. Patients will be followed up during this time and their questions will be answered.
    The intervention group benefited from the QPL and the control group received routine care. The QPL was an organized list of questions that clients could ask their answers at the next appointment with their physician or answer through the WhatsApp messenger, Soroush, And Eita. Patients were followed up during that time and their questions were answered.
    گروه مداخله از لیست آماده سوالات بهره خواهد برد و گروه کنترل مراقبت معمول را دریافت خواهد کرد. لیست آماده سوالات، یک لیست سازمان‌یافته از سؤالاتی خواهد بود که مددجویان می‌توانند پاسخ آن را در ملاقات بعدی از پزشک خود بپرسند یا پاسخ آن را از طریق پیام رسان واتس اپ، سروش و ایتا دریافت کنند. بیماران در طول این زمان پیگیری شده و به سوالات آنان پاسخ داده خواهد شد.
    گروه مداخله از لیست آماده سوالات بهره برد و گروه کنترل مراقبت معمول را دریافت کرد. لیست آماده سوالات، یک لیست سازمان‌یافته از سؤالاتی بود که مددجویان می‌توانستند پاسخ آن را در ملاقات بعدی از پزشک خود بپرسند یا پاسخ آن را از طریق پیام رسان واتس اپ، سروش و ایتا دریافت کنند. بیماران در طول این زمان پیگیری شدند و به سوالات آنان پاسخ داده شد.
  • General information

    Single blinded
    Not blinded
    1
    empty
    46
    empty
    2019-09-23, 1398/07/01
    empty
    2020-11-14, 1399/08/24
    empty
    2020-11-14, 1399/08/24
    The researcher went to the sampling site within a month but the patient was not found who have the inclusion criteria. Given that this study relates to the master's thesis and has a time limit, the research team decided to change the study group and the inclusion criteria. The website (www.randomizer.org) will also be used to facilitate random sequence generation.
    After the researcher entered the research environment, based on the objectives of the study, the eligibility criteria changed slightly. Besides, the study needs to be updated and the results added. Due to the circumstances, blinding was not possible. Sampling dates added.
    پژوهشگر به محیط نمونه گیری مراجعه کرد اما بیماری که معیارهای ورود را داشته باشددر مدت یکماه یافت نشد. با توجه به اینکه این مطالعه مربوط به پایان نامه کارشناسی ارشد است و محدودیت زمانی دارد، تیم تحقیق بر آن شد که گروه مورد مطالعه و معیار های ورود را تغییر دهد. همچنین جهت سهولت در تولید توالی تخصیص تصادفی از وب سایت(www.randomizer.org) استفاده خواهد شد.
    پس از ورود پژوهشگر به محیط پژوهش، بر اساس اهداف مطالعه، معیار های شایستگی کمی تغییر کردند. به علاوه، پس از اتمام مطالعه نیاز به به روز رسانی و اضافه کردن نتایج بود. بر اساس شرایط، امکان کورسازی وجود نداشت. تاریخ های مربوط به نمونه گیری اضافه شدند.
    Ability to read and write the Persian language
    To receive for chemotherapy, radiation therapy or both
    Age 18 and above
    Patient's willingness to participate in research
    Knowledge of breast cancer diagnosis for itself
    able to read and write Persian
    patients with breast cancer who were referred for adjuvant/ neoadjuvant treatment following tumor resection
    age 18 years or older
    knowing their diagnosis of breast cancer
    توانایی خواندن و نوشتن زبان فارسی
    دریافت پیشنهاد ادامه درمان با شیمی درمانی، رادیو تراپی و یا هر دوی آنها
    سن 18 سال و بالاتر
    تمایل مددجو به مشارکت در پژوهش
    اطلاع از تشخیص سرطان پستان برای خود
    توانایی خواندن و نوشتن زبان فارسی
    بیماران مراجعه کننده برای درمان adjuvant و neoadjuvant (بعد از جراحی برداشت تومور)
    سن 18 سال و بالاتر
    اطلاع از تشخیص سرطان پستان برای خود
    Patient's reluctance to continue to collaborate in research
    Mental illness that impedes participation in decision making or informed consent
    a history of psychiatric illness that would prevent them from participating in treatment decision-making,
    metastatic breast cancer,
    reluctance to participate in research
    عدم تمایل مددجو به ادامه همکاری در پژوهش
    ابتلا به بیماری های روانی که مانع مشارکت در تصمیم گیری یا دادن رضایت آگاهانه شوند
    ابتلا به بیماری های روانی که مانع از استقلال در تصمیم گیری برای درمان خود شود
    ابتلا به سرطان متاستاتیک پستان
    عدم تمایل به شرکت در مطالعه
    This study will be single blind. Data from two groups will be coded and delivered to the statistical analyst.
    این مطالعه، یک سوکور خواهد بود. بدین صورت که داده های مربوط به دو گروه کدگذاری شده به تحلیل گر آماری تحویل داده می شوند.
  • Intervention groups

    #1
    The intervention group will receive QPLs with questions about chemotherapy, radiotherapy, or a combination of both, depending on what the patient needs from the physician. The time taken for QPL to make decisions is different in terms of the referral time of each patient and is measured as an auxiliary variable and controlled in statistical analysis. The researcher will respond to patient questions through a social network and will follow them up. Patients meet radiologist and share their opinion with her and the final decision is made.
    The intervention group received QPLs with questions about chemotherapy, radiotherapy, or a combination of both, depending on what the patient needed. The time taken for QPL to make decisions was different in terms of the referral time of each patient and was measured as an auxiliary variable. The researcher responded to patient questions through a social network and followed them up. Patients met radiologist and shared their opinion with her and the final decision was made.
    گروه مداخله: گروه مداخله بر اساس اینکه بیمار از نظر پزشک به چه درمانی نیاز دارد QPL را با محتوی سوالاتی در مورد شیمی درمانی یا رادیوتراپی یا ترکیبی از هر دو دریافت می کند. مدت زمان در اختیار گرفتن QPL تا تصمیم گیری، برحسب زمان مراجعه هر بیمار متفاوت است و به عنوان یک متغیر کمکی اندازه گیری می شود و در تحلیل آماری اثر آن کنترل می شود. پژوهشگر از طریق محیط یکی از شبکه های اجتماعی به سوالات بیماران پاسخ داده و آن ها را پیگیری خواهد کرد. بیماران با رادیوانکولوژیست ملاقات کرده و نظر خود را با او در میان می گذارند و تصمیم نهایی گرفته می شود.
    گروه مداخله: گروه مداخله بر اساس اینکه بیمار از نظر پزشک به چه درمانی نیاز دارد QPL را با محتوی سوالاتی در مورد شیمی درمانی یا رادیوتراپی یا ترکیبی از هر دو دریافت کرد. مدت زمان در اختیار گرفتن QPL تا تصمیم گیری، برحسب زمان مراجعه هر بیمار متفاوت بود و به عنوان یک متغیر کمکی اندازه گیری شد. پژوهشگر از طریق محیط یکی از شبکه های اجتماعی و یا به صورت حضوری به سوالات بیماران پاسخ داد و آن ها را پیگیری کرد. بیماران با رادیوانکولوژیست ملاقات کردند و نظر خود را با او در میان گذاشتند و تصمیم نهایی اعلام شد.
    #2
    Control group: The control group will benefit from routine care and will not receive any interventions to help making decision .
    Control group: The control group benefited from routine care and did not receive any intervention to help making decision .
    گروه کنترل: گروه کنترل از مراقبت معمول بهره مند می شود و هیچ مداخله ای برای کمک به تصمیم گیری دریافت نخواهد کرد.
    گروه کنترل: گروه کنترل از مراقبت معمول بهره مند شد و هیچ مداخله ای برای کمک به تصمیم گیری دریافت نکرد.
  • Person responsible for general inquiries


    Name of organization / entity - English:
    Name of organization / entity - Persian:
    Full name of responsible person - English: Zahra Yazdani
    Full name of responsible person - Persian: زهرا یزدانی
    Position - English: Student of community health nursing/Master of Sciences
    Position - Persian: دانشجوی کارشناسی ارشد پرستاری سلامت جامعه
    Latest degree: bachelor
    Area of specialty/work: 27
    Area of specialty/work title - English:
    Area of specialty/work title - Persian:
    Street address - English: School of Nursing and Midwifery, Nosrat St., Tohid Sq., Tehran, Iran
    Street address - Persian: تهران، میدان توحید، خیابان نصرت، دانشکده پرستاری و مامایی
    City - English: Tehran
    City - Persian: تهران
    Province: Tehran
    Province - English:
    Province - Persian:
    contact.provinces_available: 1
    Country: Iran (Islamic Republic of)
    Postal code: 1419733171
    Phone: +98 21 6642 1685
    Mobile: +98 930 806 4360
    Fax:
    Email: zy.nurse@gmail.com
    Web page address:

    Name of organization / entity - English:
    Name of organization / entity - Persian:
    Full name of responsible person - English: Zahra Yazdani
    Full name of responsible person - Persian: زهرا یزدانی
    Position - English: Student of community health nursing/Master of Sciences
    Position - Persian: دانشجوی کارشناسی ارشد پرستاری سلامت جامعه
    Latest degree: master
    Area of specialty/work: 27
    Area of specialty/work title - English:
    Area of specialty/work title - Persian:
    Street address - English: School of Nursing and Midwifery, Nosrat St., Tohid Sq., Tehran, Iran
    Street address - Persian: تهران، میدان توحید، خیابان نصرت، دانشکده پرستاری و مامایی
    City - English: Tehran
    City - Persian: تهران
    Province: Tehran
    Province - English:
    Province - Persian:
    contact.provinces_available: 1
    Country: Iran (Islamic Republic of)
    Postal code: 1419733171
    Phone: +98 21 6642 1685
    Mobile: +98 930 806 4360
    Fax:
    Email: zy.nurse@gmail.com
    Web page address:

Protocol summary

Study aim
The Effect of Using the Question Prompt List on Self-efficacy in Decision Making, Preferences in Participation and Shared Decision Making among People with Breast Cancer.
Design
The randomized controlled trial, with parallel groups
Settings and conduct
This study was carried out at the Cancer Institute of Imam Khomeini Hospital. Question Prompt list was provided to eligible patients, and finally, shared decision making, decision self-efficacy, and Preferences for participation were measured. Data, from two groups, was coded and delivered to the statistician.
Participants/Inclusion and exclusion criteria
Inclusion criteria: patients with breast cancer who were referred for adjuvant/ neoadjuvant treatment following tumor resection, knowing their diagnosis of breast cancer, able to read and write Persian; and age 18 years or older Exclusion criteria: a history of psychiatric illness that would prevent them from participating in treatment decision-making, metastatic breast cancer, and reluctance to participate in research
Intervention groups
The intervention group benefited from the QPL and the control group received routine care. The QPL was an organized list of questions that clients could ask their answers at the next appointment with their physician or answer through the WhatsApp messenger, Soroush, And Eita. Patients were followed up during that time and their questions were answered.
Main outcome variables
Shared decision making

General information

Reason for update
After the researcher entered the research environment, based on the objectives of the study, the eligibility criteria changed slightly. Besides, the study needs to be updated and the results added. Due to the circumstances, blinding was not possible. Sampling dates added.
Acronym
IRCT registration information
IRCT registration number: IRCT20190626044032N1
Registration date: 2019-07-16, 1398/04/25
Registration timing: prospective

Last update: 2021-01-27, 1399/11/08
Update count: 3
Registration date
2019-07-16, 1398/04/25
Registrant information
Name
Zahra Yazdani
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 6642 1685
Email address
z-yazdani@razi.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-07-23, 1398/05/01
Expected recruitment end date
2019-12-22, 1398/10/01
Actual recruitment start date
2019-09-23, 1398/07/01
Actual recruitment end date
2020-11-14, 1399/08/24
Trial completion date
2020-11-14, 1399/08/24
Scientific title
The Effect of Using the Question Prompt List on Self-efficacy in Decision Making, Preferences in Participation and Shared Decision Making among People with Breast Cancer.
Public title
The Effect of Using the Question Prompt List on Self-efficacy in Decision Making, Preferences in Participation and Shared Decision Making among People with Breast Cancer.
Purpose
Education/Guidance
Inclusion/Exclusion criteria
Inclusion criteria:
able to read and write Persian patients with breast cancer who were referred for adjuvant/ neoadjuvant treatment following tumor resection age 18 years or older knowing their diagnosis of breast cancer
Exclusion criteria:
a history of psychiatric illness that would prevent them from participating in treatment decision-making, metastatic breast cancer, reluctance to participate in research
Age
From 18 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 50
Actual sample size reached: 46
Randomization (investigator's opinion)
Randomized
Randomization description
The random allocation will include three steps: Random sequence generation, allocation concealment and doing a random allocation process. Four random blocks are used to generate random sequences. Random sequence generation by block method will be done using Random Allocation Software. To ensure that random sequence is not predictable for the researcher who will perform the sampling, allocation concealment will be performed using numbered, sealed, opaque envelopes. These two steps are taken by the supervisor and the student who performs the sampling will not be involved in these two phases.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Tehran University of Medical Sciences
Street address
Sixth floor, Central Office of Tehran University of Medical Sciences, Corner of Quds St, Keshavarz Blvd
City
Tehran
Province
Tehran
Postal code
1417653761
Approval date
2019-06-26, 1398/04/05
Ethics committee reference number
IR.TUMS.VCR.REC.1398.359

Health conditions studied

1

Description of health condition studied
Breast cancer
ICD-10 code
C50
ICD-10 code description
Malignant neoplasm of breast

Primary outcomes

1

Description
Shared decision making
Timepoint
After intervention
Method of measurement
The 9-item Shared Decision Making Questionnaire

Secondary outcomes

1

Description
Self-efficacy in Decision Making
Timepoint
Before and after intervention
Method of measurement
Decision Self-efficacy Scale

2

Description
Preferences in Participation
Timepoint
Before and after intervention
Method of measurement
Control Preferences Scale

Intervention groups

1

Description
The intervention group received QPLs with questions about chemotherapy, radiotherapy, or a combination of both, depending on what the patient needed. The time taken for QPL to make decisions was different in terms of the referral time of each patient and was measured as an auxiliary variable. The researcher responded to patient questions through a social network and followed them up. Patients met radiologist and shared their opinion with her and the final decision was made.
Category
Other

2

Description
Control group: The control group benefited from routine care and did not receive any intervention to help making decision .
Category
N/A

Recruitment centers

1

Recruitment center
Name of recruitment center
Cancer Institute of Imam Khomeini Hospital
Full name of responsible person
Marzieh Lashkari
Street address
Cancer Institute, Imam Khomeini Hospital Complex, Keshavarz Blvd, Tehran
City
Tehran
Province
Tehran
Postal code
158-13145
Phone
+98 21 6658 1524
Email
crc@tums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Reza Negarandeh
Street address
Sixth floor, Central Office of Tehran University of Medical Sciences, Corner of Quds St, Keshavarz Blvd
City
Tehran
Province
Tehran
Postal code
1417653761
Phone
+98 21 8163 3619
Email
rmo@tums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Zahra Yazdani
Position
Student of community health nursing/Master of Sciences
Latest degree
Master
Other areas of specialty/work
Nursery
Street address
School of Nursing and Midwifery, Nosrat St., Tohid Sq., Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6642 1685
Email
zy.nurse@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Reza Negarandeh
Position
Professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
School of Nursing and Midwifery, Nosrat St., Tohid Sq., Tehran, Iran.
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6642 1685
Email
negarandeh@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Zahra Yazdani
Position
Student of community health nursing/Master of Sciences
Latest degree
Bachelor
Other areas of specialty/work
Nursery
Street address
School of Nursing and Midwifery, Nosrat St., Tohid Sq., Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1419733171
Phone
+98 21 6642 1685
Email
zy.nurse@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
Title and more details about the data/document
The outcomes and basic characteristics of the participants will be shared after being unidentified.
When the data will become available and for how long
Data will be released when the results are published.
To whom data/document is available
All people will have access to published data.
Under which criteria data/document could be used
Data can be used for people who intend to write systematic review and meta-analysis.
From where data/document is obtainable
To receive the data, you can send an email to the following address: zy.nurse@gmail.com
What processes are involved for a request to access data/document
After reviewing the request, the data will be sent by email.
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