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Study aim
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Evaluation of the impact of SVF cells in the effectiveness of Nanofat on acne scar healing
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Design
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This study will be a randomized single-blind clinical trial on 10 patients. Target population is patients with facial acne scars who referred to a dermatology clinic in 1399.
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Settings and conduct
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In these patients, after preparing SVF and Nanofat by taking 100 ccs of fat from the thigh area, the scars on one side of the face are treated with Nanofat, which is, in fact, the control group, and the scars on the other side are treated with Nanofat and SVF together, which is the intervention group. Post-treatment evaluation of patients three months after the intervention is performed as follows:
1)Evaluation of the change in scar size based on the digital re-imaging
2)Evaluating the extent of Neoclagenesis by ultrasound.
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: being infected with two to three-grade acne scars Fits Patrick type IV to V
Exclusion criteria: Age under 18 years old, being under treatment with anticoagulants or steroids, active skin or systemic infection, malignancy or history of chemotherapy, breastfeeding or pregnancy, history of receiving any analgesic drugs in the last week before the intervention.
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Intervention groups
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In patients with acne scars, after preparing SVF and Nanofat by taking 100 ccs of fat from the thigh area, the scars on one side of the face are treated with Nanofat, which is, in fact, the control group, and the scars on the other side are treated with Nanofat and SVF together, which is the intervention group.
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Main outcome variables
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Neoclagenesis, size of the acne scar and scar grade changes