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Protocol summary
The purpose of the present study to evaluate the effects of mulligan stretching (knee extension hamstring flexibility) and proprioceptive exercises in knee OA patients and effect of exercises to relive pain, stiffness and improve range of motion and functional ability of patients suffering from knee OA.
The purpose of the present study to evaluate the synergistic effects of Mulligan Traction Straight Leg Raise Stretch and proprioceptive exercises in knee OA patients and effect of exercises to relive pain, stiffness and improve range of motion and functional ability of patients suffering from knee OA.
The purpose of the present study to evaluate the synergistic effects of mulligan stretching (knee extension hamstring flexibility)Mulligan Traction Straight Leg Raise Stretch and proprioceptive exercises in knee OA patients and effect of exercises to relive pain, stiffness and improve range of motion and functional ability of patients suffering from knee OA.
The randomized clinical trial, double-blinded study used to investigate the effect of propioceptive and mulligan exercises in knee osteoarthritis. The study will be conducted under the strict supervision of pharmacist, physiotherapist, radiologist and medical doctor.
The randomized clinical trial, double-blinded study use to investigate the effect of propioceptive and mulligan exercises in knee osteoarthritis.
The randomized clinical trial, double-blinded study useduse to investigate the effect of propioceptive and mulligan exercises in knee osteoarthritis. The study will be conducted under the strict supervision of pharmacist, physiotherapist, radiologist and medical doctor.
Conducted at Muhammad physical therapy clinic and rehabilitation centre, Multan, Pakistan.
Conduct at Muhammad physical therapy clinic and rehabilitation centre, Multan, Pakistan.
ConductedConduct at Muhammad physical therapy clinic and rehabilitation centre, Multan, Pakistan.
Inclusion criteria: 1) Age 35-65 years
2) Patients with diagnosed OA
3) Both genders
4) Patients with swelling in knee joints
5) Patients with pain in knee joints
6) Patients having difficulty in walking and climbing stairs
Exclusion criteria: 1) Vascular neoplasia
2) Fibromyalgia
4) Radiculopathy
5) Neuropathy
6) Tumor
7) Joint fractures
8) Vestibular problems
9) Congenital disorders
Inclusion criteria: 1) Age 40-65 years
2) Patients with diagnosed OA
3) Both genders
4) Patients with swelling in knee joints
5) Patients with pain in knee joints
6) Patients having difficulty in walking and climbing stairs
Exclusion criteria: 1) Vascular neoplasia
2) Fibromyalgia
4) Radiculopathy
5) Neuropathy
6) Tumor
7) Joint fractures
8) Vestibular problems
9) Congenital disorders
Inclusion criteria: 1) Age 3540-65 years 2) Patients with diagnosed OA 3) Both genders 4) Patients with swelling in knee joints 5) Patients with pain in knee joints 6) Patients having difficulty in walking and climbing stairs Exclusion criteria: 1) Vascular neoplasia 2) Fibromyalgia 4) Radiculopathy 5) Neuropathy 6) Tumor 7) Joint fractures 8) Vestibular problems 9) Congenital disorders
Treatment group A- Treatment regimem is distributed in 6-week period thrice per week exercise sessions lasted for 30 minutes treated with proprioceptive exercises: standing on one leg, knee flexion and extension exercises (sitting position with a chair and Thera Band), walking on heel and toes (with eyes open and closed), half squat). This will increase muscle strength thus decreasing pain and stiffness. Treatment regime distributed in 6-week period twice per week exercise sessions lasted for 15 minutes in group B treated with Mulligan stretching exercise (knee extension hamstrings flexibility). This will increase muscle strength.
Group A will receive proprioceptive exercises, half squats, standing on just one foot, walking on the heel and toes, one-legged balance exercises and knee flexion and extension exercises while sat in a chair. Proprioceptive Exercise will be given 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes. Every exercise will be done for 1 to 2 minutes, with a 30-second break in between. Participants in the Mulligan Traction Straight Leg Raise Stretch group B will be the intervention 3 times a week for 30 minutes each session. Every session was involved performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. Whereas Group C will be given both proprioceptive and MT-SLR.
Treatment groupGroup A- Treatment regimem is distributed in 6-week period thrice per week exercise sessions lasted for 30 minutes treated with will receive proprioceptive exercises:, half squats, standing on just one legfoot, walking on the heel and toes, one-legged balance exercises and knee flexion and extension exercises (sitting positionwhile sat in a chair. Proprioceptive Exercise will be given 3 sessions/week for 8 weeks, with a chair and Thera Band)total of 24 sessions, walking on heel and toes (with eyes open and closed), half squat)each lasting 45 minutes. ThisEvery exercise will increase muscle strength thus decreasing pain and stiffness. Treatment regime distributedbe done for 1 to 2 minutes, with a 30-second break in 6-week period twice per week exercise sessions lasted for 15 minutesbetween. Participants in the Mulligan Traction Straight Leg Raise Stretch group B treated with Mulligan stretching exercise (knee extension hamstrings flexibility)will be the intervention 3 times a week for 30 minutes each session. ThisEvery session was involved performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. Whereas Group C will increase muscle strengthbe given both proprioceptive and MT-SLR.
General information
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3540
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Only the name of the organization sponsor/ Funding source was changed.
Some changes have been made
Only the name of the organization sponsor/ Funding source was changed.Some changes have been made
MULLIGAN AND PROPRICEPTIVE EXERCISES IN KNEE OSTEOARTHRITIS
Mulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
MULLIGAN AND PROPRICEPTIVE EXERCISES IN KNEE OSTEOARTHRITISMulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
COMPARATIVE ANALYSIS OF MULLIGAN AND PROPRICEPTIVE EXERCISES IN KNEE OSTEOARTHRITIS
Therapeutic utility of Mulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
COMPARATIVE ANALYSIS OF MULLIGAN AND PROPRICEPTIVE EXERCISES IN KNEE OSTEOARTHRITISTherapeutic utility of Mulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
Age 35-65 years
Patients with diagnosed OA
Both genders
Patients with swelling in knee joints
Patients with pain in knee joints
Difficulty in walking and climbing stairs
Age 40-65 years
Patients with diagnosed OA
Both genders
Patients with swelling in knee joints
Patients with pain in knee joints
Difficulty in walking and climbing stairs
Age 3540-65 years Patients with diagnosed OA Both genders Patients with swelling in knee joints Patients with pain in knee joints Difficulty in walking and climbing stairs
Primary outcomes
#1
6 weeks
8 weeks
68 weeks
#2
6 weeks
8 weeks
68 weeks
Secondary outcomes
#1
6 weeks
8 weeks
68 weeks
Intervention groups
#1
Intervention group: Group-A Treatment regimem is distributed in 6-week period thrice per week exercise sessions lasted for 30 minutes in group A treated with proprioceptive exercises: standing on one leg, knee flexion and extension exercises (sitting position with a chair and TheraBand), walking on heel and toes (with eyes open and closed), half squat). This will increase muscle strength thus decreasing pain and stiffness.
Intervention group: Group A will receive proprioceptive exercises, half squats, standing on just one foot, walking on the heel and toes (with eyes open and closed), one-legged balance exercises using a heating pad, and knee flexion and extension exercises while sat in a chair. Proprioceptive Exercise group A will be given 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes. The exercises in their program will develop from static to dynamic, including single-leg stances and balance exercises on unstable surfaces, starting with low-to-moderate intensity balance and stability exercises. Every exercise will be done for 1 to 2 minutes, with a 30-second break in between.
Intervention group: Group-A Treatment regimem is distributed in 6-week period thrice per week exercise sessions lasted for 30 minutes in group A treated withwill receive proprioceptive exercises:, half squats, standing on just one leg, knee flexion and extension exercises (sitting position with a chair and TheraBand)foot, walking on the heel and toes (with eyes open and closed), half squat)one-legged balance exercises using a heating pad, and knee flexion and extension exercises while sat in a chair. ThisProprioceptive Exercise group A will increase muscle strength thus decreasing painbe given 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes. The exercises in their program will develop from static to dynamic, including single-leg stances and stiffnessbalance exercises on unstable surfaces, starting with low-to-moderate intensity balance and stability exercises. Every exercise will be done for 1 to 2 minutes, with a 30-second break in between.
#2
Intervention group: Group-B Treatment regimen distributed in 6-week period twice per week exercise sessions lasted for 15 minutes in group B treated with Mulligan stretching exercise (knee extension hamstrings flexibility). This will increase muscle strength.
Intervention group: Group-B The total treatment regimen will be 8 weeks, including 24 sessions, participants in the Mulligan Traction Straight Leg Raise Stretch (MT-SLR) group B get the intervention 3 times a week for 30 minutes each session. Every session will involve performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. The traction force will be adjusted according to each individual's comfort level and the repetitions were held for 15–20 seconds each.
Intervention group: Group-B TreatmentThe total treatment regimen distributedwill be 8 weeks, including 24 sessions, participants in 6the Mulligan Traction Straight Leg Raise Stretch (MT-week period twice per week exercise sessions lasted for 15 minutes inSLR) group B treated with Mulligan stretching exercise (knee extension hamstrings flexibility)get the intervention 3 times a week for 30 minutes each session. ThisEvery session will increase muscle strengthinvolve performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. The traction force will be adjusted according to each individual's comfort level and the repetitions were held for 15–20 seconds each.
#3
empty
Treatment - Other
treatment-other
empty
Intervention group: Group C will be given both proprioceptive and MT-SLR The total treatment regimen will be 8 weeks, including 24 sessions, participants in the Mulligan Traction Straight Leg Raise Stretch (MT-SLR) get the intervention 3 times a week for 30 minutes each session. Proprioceptive Exercise group will be given in 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes.
Intervention group: Group C will be given both proprioceptive and MT-SLR The total treatment regimen will be 8 weeks, including 24 sessions, participants in the Mulligan Traction Straight Leg Raise Stretch (MT-SLR) get the intervention 3 times a week for 30 minutes each session. Proprioceptive Exercise group will be given in 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes.
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گروه مداخله:
گروه مداخله:
Protocol summary
Study aim
The purpose of the present study to evaluate the synergistic effects of Mulligan Traction Straight Leg Raise Stretch and proprioceptive exercises in knee OA patients and effect of exercises to relive pain, stiffness and improve range of motion and functional ability of patients suffering from knee OA.
Design
The randomized clinical trial, double-blinded study use to investigate the effect of propioceptive and mulligan exercises in knee osteoarthritis.
Settings and conduct
Conduct at Muhammad physical therapy clinic and rehabilitation centre, Multan, Pakistan.
Participants/Inclusion and exclusion criteria
Inclusion criteria: 1) Age 40-65 years
2) Patients with diagnosed OA
3) Both genders
4) Patients with swelling in knee joints
5) Patients with pain in knee joints
6) Patients having difficulty in walking and climbing stairs
Exclusion criteria: 1) Vascular neoplasia
2) Fibromyalgia
4) Radiculopathy
5) Neuropathy
6) Tumor
7) Joint fractures
8) Vestibular problems
9) Congenital disorders
Intervention groups
Group A will receive proprioceptive exercises, half squats, standing on just one foot, walking on the heel and toes, one-legged balance exercises and knee flexion and extension exercises while sat in a chair. Proprioceptive Exercise will be given 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes. Every exercise will be done for 1 to 2 minutes, with a 30-second break in between. Participants in the Mulligan Traction Straight Leg Raise Stretch group B will be the intervention 3 times a week for 30 minutes each session. Every session was involved performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. Whereas Group C will be given both proprioceptive and MT-SLR.
Main outcome variables
Increase in ROM and functional ability, decrease in pain and inflammatory load in body.
General information
Reason for update
Some changes have been made
Acronym
IRCT registration information
IRCT registration number:IRCT20230202057310N2
Registration date:2023-08-29, 1402/06/07
Registration timing:prospective
Last update:2024-09-25, 1403/07/04
Update count:3
Registration date
2023-08-29, 1402/06/07
Registrant information
Name
Imran Ahmad Khan
Name of organization / entity
Muhammad Nawaz Shareef University of Agriculture, Multan
Country
Pakistan
Phone
+92 333 6120602
Email address
imran.ahmad@mnsuam.edu.pk
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2023-08-31, 1402/06/09
Expected recruitment end date
2024-03-02, 1402/12/12
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Therapeutic utility of Mulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
Public title
Mulligan traction straight leg raise stretch and proprioceptive exercise in treating osteoarthritis
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Age 40-65 years
Patients with diagnosed OA
Both genders
Patients with swelling in knee joints
Patients with pain in knee joints
Difficulty in walking and climbing stairs
Allocation concealment occurs and patients will be recruited by using simple randomization through the Lottery method. lottery method carried out through sealed envelopes. Also the data analyser will be kept blind to minimize biasness
Blinding (investigator's opinion)
Double blinded
Blinding description
Participants will be blinded. Participants will be unaware of the type of treatments that will be evaluated after the completion of the intervention trial. Subjects will be completely unaware of the type and effects of both interventions. And in the same way data analyser will be kept blind by not knowing about the effects and group details
Placebo
Not used
Assignment
Parallel
Other design features
Patients were assessed by radiological finding (x-ray) and by physical assessment and by monitoring of biochemical parameters
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
The Institutional Ethical Committee of Muhammad Institute of Medical and Allied Sciences, Multan
Street address
HBL street, Sbzazar metro station, Bosan road, Multan, Pakistan
City
Multan
Postal code
66000
Approval date
2023-07-30, 1402/05/08
Ethics committee reference number
MIMAS/06/26/Maliha
Health conditions studied
1
Description of health condition studied
Knee osteoarthritis with grade 1,2 and 3
ICD-10 code
M17
ICD-10 code description
Osteoarthritis of knee
Primary outcomes
1
Description
Pain and functional disability
Timepoint
8 weeks
Method of measurement
Numerical Pain Rating Scale, Pain catastrophizing scale, The Western Ontario and McMaster Universities Arthritis Index (WOMAC)
2
Description
Range of motion
Timepoint
8 weeks
Method of measurement
The Western Ontario and McMaster Universities Arthritis Index (WOMAC)
Secondary outcomes
1
Description
Inflammatory biomarkers
Timepoint
8 weeks
Method of measurement
Complete blood count (CBC) and interleukins measurement
Intervention groups
1
Description
Intervention group: Group A will receive proprioceptive exercises, half squats, standing on just one foot, walking on the heel and toes (with eyes open and closed), one-legged balance exercises using a heating pad, and knee flexion and extension exercises while sat in a chair. Proprioceptive Exercise group A will be given 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes. The exercises in their program will develop from static to dynamic, including single-leg stances and balance exercises on unstable surfaces, starting with low-to-moderate intensity balance and stability exercises. Every exercise will be done for 1 to 2 minutes, with a 30-second break in between.
Category
Treatment - Other
2
Description
Intervention group: Group-B The total treatment regimen will be 8 weeks, including 24 sessions, participants in the Mulligan Traction Straight Leg Raise Stretch (MT-SLR) group B get the intervention 3 times a week for 30 minutes each session. Every session will involve performing 3 sets of 10 repetitions of straight leg lifts while using manual traction. The traction force will be adjusted according to each individual's comfort level and the repetitions were held for 15–20 seconds each.
Category
Treatment - Other
3
Description
Intervention group: Group C will be given both proprioceptive and MT-SLR The total treatment regimen will be 8 weeks, including 24 sessions, participants in the Mulligan Traction Straight Leg Raise Stretch (MT-SLR) get the intervention 3 times a week for 30 minutes each session. Proprioceptive Exercise group will be given in 3 sessions/week for 8 weeks, with a total of 24 sessions, each lasting 45 minutes.
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Muhammad physical therapy clinic and rehabilitation center, Multan
Full name of responsible person
Maliha Khalid Khan
Street address
HBL street, near Sbzazar metro station, Bosan road, Multan, Pakistan
City
Multan
Postal code
66000
Phone
+92 312 6827130
Email
malihatareen1997@gmail.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Muhammad Nawaz Sharif University of Agriculture
Full name of responsible person
Imran Ahmad Khan
Street address
Agriculture Complex, Old Shuja Abad Rd,
City
Multan
Postal code
66000
Phone
+92 333 6120602
Email
imranahmadkhandurrani@gmail.com
Grant name
Student fund
Grant code / Reference number
08/26/2023/MNSUAM
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Muhammad Nawaz Sharif University of Agriculture
Proportion provided by this source
70
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan